et developpement

Toute l’équipe MatriceLab poursuit ses recherches dans le domaine de l’immunologie de la reproduction. De nouveaux tests et de nouvelles solutions innovantes contre l’infertilité sont développées chaque jour autour du Dr Nathalie Lédée et de Marie Petitbarat.

Nos publications

The Endometrial Immune Profiling May Positively Affect the Management Of Recurrent Pregnancy Loss

Mars 2021

Target Endometrial Scratching: An Example of Endometrial Diagnosis Usage in Reproductive Medicine.

Sept. 2020

Covid19- and immunomodulation treatment for women with reproductive failures

Juin 2020

Endometrial Immune Profiling : A method to design Personalized Care in Assisted Reproductive Medicine.

Juin 2020

Intralipids may represent a new hope for patients with reproductive failures and simltanously an over immune endometrial activation

Sept. 2018

Impact of prednisone in patients with repeated embryo implantation failures: Beneficial or deleterious?

Mars 2018

Uterine immune profiling for increasing live birth rate: A one-to-one matched cohort study

Nov. 2016

The Uterine Immune Profile May Help Women With Repeated Unexplained Embryo Implantation Failure After In Vitro Fertilization

Dec. 2015

Impediments to implantation

Juil. 2014

Préparer l’endomètre à l’implantation embryonnaire

Juin 2014

2004 - 2011

New pre-conception immune biomarkers for clinical practice: interleukin-18, interleukin-15 and TWEAK on the endometrial side, G-CSF on the follicular side.


TWEAK appears as a modulator of endometrial IL-18 related cytotoxic activity of uterine natural killers.


Tolerance to the foetal allograft


Tumor necrosis factor-like weak inducer of apoptosis (TWEAK)/fibroblast growth factor inducible-14 might regulate the effects of interleukin 18 and 15 in the human endometrium.


Uterine receptivity and cytokines: new concepts and new applications


Role of the endometrial tripod interleukin-18, -15, and -12 in inadequate uterine receptivity in patients with a history of repeated in vitro fertilization-embryo transfer failure.


Materno-foetal dialogue and human embryo implantation: some evolving concepts


A new role for natural killer cells, interleukin (IL)-12, and IL-18 in repeated implantation failure after in vitro fertilization