Infertility is not a finality!

MatriceLab’s pioneering endometrial immunology test is the result of more than 10 years of research. Combined with precision therapy, it gives women in Assisted Reproductive Therapy a better chance of successful embryo implantation.

Our mission

to increase pregnancy rates through personalized care

Our solution

The goal

Establish an immune balance profile of uterine receptivity that forms the basis for a personalized therapeutic strategy.

The test

a simple endometrial biopsy performed by your gynecologist.

The analysis

by identifying the immunological markers of the endometrium, MatriceLab proposes therapeutic avenues to favor the success of the implantation.

Our studies show a 40% to 50% birth rate, following the application of the proposed treatment, at the next embryo transfer after the MatriceLab test.

Learn more about the test

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Doctors and patients testify

We called upon MatriceLab thanks to the advice of my doctor, during a ART journey of more than 7 years and after 4 IVF failures.

Thanks to the immunological analysis of the endometrium, we were able to determine a care protocol and a strategy. The endometrial biopsy allowed us to prepare this strategy, with the use of aspegic and progesterone a few days before and after the oocyte donation.

Since then, we are the happy parents of two children born thanks to ART and especially thanks to the donor and MatriceLab.

Laëtitia et Mathieu

Our founding tream

Dr Nathalie Ledee

MD in Obstetrician Gynecologist and PhD in reproductive immunology

Dr Dominique Vitoux

Pharmacien biologiste

Alaa Kazhalawi

Ingénieur spécialisée en biologie

Marie Petitbarat

PhD in Reproductive Immunology

Katya Vezmar

Ingénieur spécialisée en biologie de la santé

Céline Holey

Secrétaire médicale

Causes of infertility

In France, infertility affects one couple out of four. The definition of the World Health Organization (WHO) is very precise:

infertility is the inability of a couple to achieve a pregnancy after twelve months of regular unprotected sexual intercourse.

This delays the age of motherhood and fatherhood, while female fertility drops from the age of 35.

Many factors can lead to female infertility as well as male infertility: endometriosis, polycystic ovarian syndrome, tubal problems, decrease in sperm concentration or motility in the semen (it has decreased by half since the 1970s).

In 10% of cases, no cause is found. In addition, 5% of women of childbearing age have recurrent miscarriages.

Advances in research and the commitment of the public authorities, with the first national plan to combat infertility, now provide couples with numerous solutions to overcome infertility.

Causes of ART failure

The causes

The causes of failure can be multiple during an ART process, at the time of fertilization or implantation.

The origin

An embryo implantation failure can be of embryonic origin with genetic causes or of uterine or immunological origin.

The factors

The apposition, adhesion and invasion of the uterus by the embryo are subject to numerous systemic factors linked to the environment that we are beginning to understand better.

The Test

The MatriceLab test aims at analyzing the uterine immunological factors in order to propose personalized solutions that favor the adhesion and development of the embryo at the time of its implantation.

News

Research and development

The MatriceLab team continues its research and development work to fight against infertility and to accompany patients and couples in their life projects. As an independent research and innovation laboratory, MatriceLab is developing an ever more complete and efficient pathway for the distribution of its first diagnostic test to the greatest number of people throughout France and internationally.

The team is also working on the development of new diagnostic tests and procedures in the field of women’s health to pursue research efforts in reproductive immunology.